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Preheat your oven to 350° F. Line a rimmed sheet pan with foil.
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In a large bowl, whisk together the egg, salt, pepper, garlic powder, onion powder, and thyme.
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Add the ground beef, almond flour, and Parmesan. Gently mix, just until uniform.
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Shape the mixture into a rectangular loaf and place it on the prepared baking sheet. Brush the loaf with ketchup.
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Bake the meatloaf until the center of the loaf registers 160° F, 50-60 minutes.
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Rest the meat for 15 minutes before slicing and serving.
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